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April 25, 2012 The latest Curves research was presented at the 2012 Experimental Biology Annual Meeting on April 25, 2012 in San Diego, CA. The abstracts below and 2012 FASEB Poster Presentations summarize results from a comparitive effectiveness trial that evaluated the efficacy of following several popular weight loss programs for 12-weeks (Curves 90 Challenge, Weight Watchers® Points Plus, Jenny Craig®, and Nutrisystem® Advance Select™). Results indicated that the Curves program promoted significantly more fat loss and percent body fat loss. In addition, the Curves program promoted greater gains in fitness, some health markers, and perception of general health improvement compared to these other diet programs. Comparison of the efficacy of popular weight loss programs in sedentary overweight women I: body composition and resting energy expenditure 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) were randomized to participate in a control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® Points Plus (WW), Jenny Craig® (JC), or Nutrisystem® Advance Select™ (NS) weight loss programs for 12-wks. Body mass, DEXA body composition, and resting energy expenditure (REE) measurements were obtained at 0, 4, 8, & 12 wks and analyzed by MANOVA. Data are presented as changes from baseline after 12-wks. Participants in the diet groups lost similar amounts of body mass (C -0.1±3.1; CC -5.1±4.2; WW -4.0±3.4; JC -5.3±3.8; NS -5.1±4.5 kg, p=0.001). However, participants in the CC group experienced significantly greater loss in fat mass (C -0.1±3.1; CC -4.2±4.0; WW -2.2±2.7; JC -3.5±3.3; NS -2.3±2.5 kg, p=0.001), less loss in FFM (C -0.0±2.2; CC -0.6±2.4; WW -1.6±2.1; JC -1.8±2.1; NS -2.4±2.2 kg, p=0.001), and greater reductions in percent body fat (C 0.03±1.7; CC -2.9±3.6; WW -0.8±2.4; JC -1.4±2.4; -0.2±1.7%, p=0.001). No significant differences were observed among groups in changes in REE (C 36±195; CC -96±180; WW -93±147; JC -21±212; -49±207 kcal/d, p=0.37). Results indicate that participation in the CC program promotes more favorable changes in body composition than participation in other popular weight loss programs. Supported by Curves International (Waco, TX) Comparison of the efficacy of popular weight loss programs in sedentary overweight women II: health & fitness markers 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) were randomized to participate in a no diet or exercise control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® Points Plus (WW), Jenny Craig® (JC), or Nutrisystem® Advance Select™ (NS) weight loss programs for 12-wks. Data were analyzed by ANOVA and are presented as percent changes from baseline after 12-wks. Participants in diet groups had greater changes in waist (C 2.1±6.6; CC -3.8±5.5; WW -4.0±5.7; JC -3.7±3.3; NS -2.9±6.3 %, p=0.008) and hip circumference (C 0.8±3.2; CC -4.9±4.6; WW -2.7±2.8; JC -5.1±4.4; NS -4.1±4.0 %, p=0.001) with no differences among diet groups. Resting HR, SBP, and DBP decreased over time with no differences observed among groups. Changes in relative peak VO2 (C -2.2±10; CC 15.4±17; WW 7.4±19; JC 8.1±11; NS 3.8±7 %, p=0.001) and 1 RM bench press (C -1.1±14; CC 9.3±13; WW 4.7±15; JC 5.4±14; NS -3.7±15 %, p=0.01) were greater in the CC group while changes in 1RM leg press (C 13.7±24; CC 16.1±22; WW 3.6±20; JC 0.5±23; NS 3.7±24 %, p=0.07) and leg press endurance (C 8.4±36; CC 47.3±120; WW -4.5±45; JC 6.0±56; NS 1.8±46 %, p=0.07) tended to be greater in the CC group. Results indicate that participation in the CC program promotes more favorable changes in markers of fitness than other popular weight loss programs. Supported by Curves International (Waco, TX) Comparison of the efficacy of popular weight loss programs in sedentary overweight women III: fasting blood lipids and glucose 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) were randomized to participate in a no diet or exercise control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® Points Plus (WW), Jenny Craig® (JC), or Nutrisystem® Advance Select™ (NS) weight loss programs for 12-wks. Fasting blood samples were obtained at 0, 4, 8, and 12 wks and analyzed by MANOVA. Data are presented as percent changes from baseline after 12-wks. Participants in the CC group had greater changes in TG (C -1.9±23; CC -8.3±28; WW -2.7±32; JC 15.1±43; NS 11.1±29 %, p=0.03) with TG levels increased in the JC and NS groups. Although some trends were observed, no significant interactions were observed among groups in total CHL (C -1.5±11; CC -5.9±9; WW 1.0±12; JC -2.3±11; NS -3.8±15 %, p=0.22), HDL-c (C -3.7±9; CC -0.6±14; WW 1.1±13; JC -5.0±16; NS -4.0±13 %, p=0.45), LDL-c (C -3.3±17; CC -7.0±9; WW 11.0±52; JC -2.7±12; NS -6.1±21 %, p=0.12), the ratio of CHL/HDL-c (C -2.4±24; CC -4.0±11; WW -0.3±13; JC 4.8±16; NS 0.1±12 %, p=0.48), or blood glucose (C -1.3±9; CC -2.4±16; WW -4.8±19; JC -1.6±10; NS -2.9±16 %, p=0.93). Results indicate that participation in the CC program promotes more favorable changes in TG levels than other popular weight loss programs and that adherence to popular diets may affect blood lipids differentially. Comparison of the efficacy of popular weight loss programs in sedentary overweight women IV: bone, protein & liver status 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) were randomized to participate in a no diet or exercise control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® Points Plus (WW), Jenny Craig® (JC), or Nutrisystem® Advance Select™ (NS) weight loss programs for 12-wks. Fasting blood samples were obtained at 0, 4, 8, and 12 wks and analyzed by MANOVA. No significant interactions were observed among control and diet groups in bone mineral area (p=0.79), bone mineral content (p=0.41), bone mineral density (p=0.39), serum calcium (p=0.60), alkaline phosphate (p=0.39), total protein (p=0.22), blood urea nitrogen (p=0.41), creatinine (p=0.20), BUN/Creatinine ratio (p=0.31), aspartate amino-transaminase (p=0.51), alanine amino-transaminase (p=0.37), total bilirubin (p=0.41), albumin (p=0.30), globulin (p=0.18), or albumin/globulin ratio (p=0.65). Changes in these bone markers did not significantly correlate to changes in protein status or liver function. Results indicate that participation in these popular diets does not negatively affect bone status, markers of protein, or liver function. Comparison of the efficacy of popular weight loss programs in sedentary overweight women V: perception of quality of diets 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) were randomized to participate in a no diet or exercise control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® Points Plus (WW), Jenny Craig® (JC), or Nutrisystem® Advance Select™ (NS) weight loss programs for 12-wks. Self-reported diet quality was assessed on a 0-10 point Likert scale at 0, 4, 8, and 12-wks. Data were analyzed by MANOVA and are presented as percent changes after 12-wks. No significant interactions were seen in changes in appetite (C -12.2±20; CC -4.0±41; WW -1.6±50; JC -14.3±27; NS -3.1±33 %, p=0.69), hunger (C -16.3±31; CC -1.2±47; WW 10.4±52; JC -0.9±47; NS 10.6±88 %, p=0.48), satisfaction with food (C -3.8±49; CC 4.3±33; WW 0.8±26; JC -3.0±34; NS 0.7±33 %, p=0.93), feelings of fullness (C -0.3±32; CC -1.1±29; WW -5.3±21; JC -10.7±37; NS 1.4±46 %, p=0.76), or general feelings of energy (C 19.4±67; CC 55.3±67; WW 56.8±88; JC 28.4±56; NS 38.9±59 %, p=0.23). Mean changes in diet quality were greater in the CC and JC groups compared to control (C 2.2±40; CC 86±79; WW 58±68; JC 99±158; NS 64±92 %, p=0.02). Results reveal that participants generally perceived satisfaction with the diets and that diet quality was significantly better in the CC and JC diet groups compared to a non-diet controls. Comparison of the efficacy of popular weight loss programs in sedentary overweight women VI: quality of life 126 sedentary women (44±12 yr, 44.8±5% body fat, 35.4±6 kg/m2) participated in a control group (C) or the Curves Complete® 90-day Challenge (CC), Weight Watchers® (WW), Jenny Craig® (JC), or Nutrisystem® (NS) weight loss programs for 12-wks. Participants completed the SF-36 quality of life inventory at 0, 4, 8, and 12-wks. Data were analyzed by MANOVA and are presented as changes after 12-wks. Changes in perception of general health were greater in the CC group (C -0.5±9; CC 12.2±14; WW 2.2±13; JC 6.3±13; NS 2.9±10, p=0.008) while physical functioning (C 3.3±18; CC 15.6±18; WW 7.5±10; JC 18.5±41; NS 2.8±11, p=0.01) and limitations due to physical problems (C -27.8±95; CC 47.9±67; WW 40.6±88; JC 23.1±70; NS 34.6±92, p=0.05) were higher in diet groups. No differences were observed among groups in limitations due to emotional problems (C 18.5±40; CC 12.5±37; WW 29.2±72; JC 16.7±92; NS 18.5±80, p=0.98), vitality (C 1.7±8; CC 11.0±14; WW 7.9±14; JC 4.2±16; NS 6.1±11, p=0.15), mental health (C 2.9±10; CC 6.0±10; WW 5.3±11; JC 2.5±11; NS 1.5±13, p=0.56), social functioning (C 2.8±7; CC 2.1±11; WW 0.4±7; JC -0.7±10; NS -0.9±10, p=0.37), or bodily pain (C 0.2±19; CC 1.8±17; WW 0.9±17; JC 6.1±19; NS 6.3±18, p=0.77). Results indicate that participation in the CC program promotes a greater increase in perception of general health when compared to controls and other popular diet programs. |